Preview for Wednesday, September 23, 2026. Schedule and player information can change.
Minnesota Twins at San Francisco Giants
The Minnesota Twins head to San Francisco to face the Giants in a matchup with modest offensive and pitching numbers on both sides. Minnesota's team wOBA sits at 0.312 compared to San Francisco's 0.308, giving the Twins a slight offensive edge on paper, though the Giants counter with a better team ERA at 4.36 versus Minnesota's 4.58. The two clubs are essentially even on FIP, with the Twins at 4.31 and the Giants at 4.32.
On the mound, Connor Prielipp starts for Minnesota with an ERA of 4.94 across approximately 120.3 innings pitched, but his FIP of 3.83 suggests better underlying performance than his ERA indicates. Cesar Perdomo takes the ball for San Francisco with a lower ERA of 3.72, though his FIP of 5.03 is worse than Prielipp's, and his sample is much smaller at approximately 19.3 innings pitched. That split between ERA and FIP for both pitchers makes the head-to-head numbers a mixed bag rather than a clear advantage for either side.
Both rosters carry notable injury designations. Mick Abel of the Twins is listed on the 60-Day IL, and Anthony Banda is listed on the 15-Day IL, while Eduardo Beltre is also listed on the 60-Day IL for Minnesota. San Francisco's list includes Willy Adames on the 10-Day IL, along with Harrison Bader and Hayden Birdsong both listed on the 60-Day IL. Weighing the team-level figures together, the Giants' edge in ERA and FIP that closely matches Minnesota's, combined with Prielipp's stronger FIP against Perdomo's higher FIP despite the lower ERA, leaves the statistical picture fairly balanced with Minnesota holding a slight offensive edge in wOBA.
Statistical scope: MLB Stats API; 2026 regular season season-to-date; exact statistical through-date not supplied.
WP selection: Giants +1.5. Confidence: Slight Lean.
The selection is supplied separately by WP. The comparisons above do not establish why the model made this selection.
WP home-run candidate for Giants: Victor Bericoto. The selection uses roster and season-stat inputs; it does not establish a confirmed batting lineup or favourable betting odds.
WP home-run candidate for Twins: Emmanuel Rodriguez. The selection uses roster and season-stat inputs; it does not establish a confirmed batting lineup or favourable betting odds.
Predictions are uncertain; no outcome is guaranteed. Check the picks page for the latest available selections.