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MLB Predictions for September 29, 2026: Every Game Previewed

2026-09-29 · Posted at 9:40 AM ET

Preview for Tuesday, September 29, 2026. Schedule and player information can change.

Philadelphia Phillies at Atlanta Braves

Philadelphia sends Jesús Luzardo to the mound against Atlanta's Chris Sale in a matchup of two starters who have been sharp all season. Luzardo carries a 2.86 ERA and a 2.85 FIP over approximately 179.7 innings pitched, while Sale checks in with an even lower 2.16 ERA and 2.36 FIP across roughly 162.7 innings. Both marks point to strong run prevention, but Sale's numbers are the better of the two in both ERA and FIP.

On the team side, Atlanta holds a slight offensive edge with a WP-estimated wOBA of 0.311 compared to Philadelphia's 0.307, though the Phillies actually post the better team FIP at 3.86 against the Braves' 4.20. Atlanta's team ERA of 3.63 is lower than Philadelphia's 4.04, suggesting the Braves' pitching staff overall has prevented runs more effectively even with a less favorable FIP figure.

Both clubs list several players on extended injury statuses. Rayven Antonio, Starlyn De La Cruz and Bryce Elder appear on Atlanta's injury report, while Adolis Garcia, Connor Gillispie and Brad Keller are listed for Philadelphia. Taken together, the pitching matchup and team run-prevention figures lean toward Atlanta, with Sale's superior ERA and FIP against Luzardo the headline factor.

Statistical scope: MLB Stats API; 2026 regular season season-to-date; exact statistical through-date not supplied.

WP selection: Phillies +1.5. Confidence: Slight Lean.

The selection is supplied separately by WP. The comparisons above do not establish why the model made this selection.

WP home-run candidate for Braves: Ronald Acuña Jr.. The selection uses roster and season-stat inputs; it does not establish a confirmed batting lineup or favourable betting odds.

WP home-run candidate for Phillies: Bryce Harper. The selection uses roster and season-stat inputs; it does not establish a confirmed batting lineup or favourable betting odds.

Chicago White Sox at Houston Astros

Chicago's Hagen Smith takes the ball against Houston's AJ Blubaugh in a start where the sample sizes differ notably. Smith has thrown approximately 28.0 innings with a 1.29 ERA and 2.42 FIP, while Blubaugh has logged about 96.0 innings with a 3.66 ERA and 4.38 FIP. Smith's rate numbers are considerably stronger, though his innings total is much smaller than Blubaugh's.

At the team level, the two clubs are closely matched offensively, with Houston's WP-estimated wOBA of 0.317 just ahead of Chicago's 0.316. On the run-prevention side, the White Sox hold better team figures across the board, posting a 4.12 ERA and 4.32 FIP compared to the Astros' 4.45 ERA and 4.59 FIP.

Injury notes include Brooks Baldwin, Joey Bart and Aldrin Batista for the White Sox, and Brandon Bielak, Jax Biggers and Drew Brutcher for the Astros. Between the starters and the team-wide pitching marks, Chicago's numbers look somewhat stronger overall, led by Smith's sharp ERA and FIP and the White Sox's better team ERA and FIP figures.

Statistical scope: MLB Stats API; 2026 regular season season-to-date; exact statistical through-date not supplied.

WP selection: White Sox moneyline. Confidence: Confident.

The selection is supplied separately by WP. The comparisons above do not establish why the model made this selection.

WP home-run candidate for Astros: Lucas Spence. The selection uses roster and season-stat inputs; it does not establish a confirmed batting lineup or favourable betting odds.

WP home-run candidate for White Sox: Randal Grichuk. The selection uses roster and season-stat inputs; it does not establish a confirmed batting lineup or favourable betting odds.

Boston Red Sox at New York Yankees

Boston's Payton Tolle and New York's Cam Schlittler headline a pitching matchup with both starters working deep into the season. Tolle has a 3.03 ERA and 3.11 FIP over approximately 148.7 innings, while Schlittler has been even better with a 1.95 ERA and 2.63 FIP across roughly 193.7 innings. Schlittler's figures are the stronger of the two in both categories.

The team statistics show the two offenses are essentially even, with Boston and New York each carrying a WP-estimated wOBA of 0.312. On run prevention, New York's team ERA of 3.24 is lower than Boston's 3.54, though Boston's team FIP of 3.72 is slightly better than the Yankees' 3.78, making the pitching comparison a mixed picture at the team level.

Several players are listed on injury reports for both sides. Angel Benitez, Kervin Castro and Fernando Cruz appear for New York, while Kristian Campbell, Triston Casas and Kutter Crawford are listed for Boston. Given Schlittler's lower ERA and FIP against Tolle, along with New York's better team ERA, the available figures tilt toward the Yankees in this matchup.

Statistical scope: MLB Stats API; 2026 regular season season-to-date; exact statistical through-date not supplied.

WP selection: Yankees moneyline. Confidence: Confident.

The selection is supplied separately by WP. The comparisons above do not establish why the model made this selection.

WP home-run candidate for Red Sox: Wilyer Abreu. The selection uses roster and season-stat inputs; it does not establish a confirmed batting lineup or favourable betting odds.

WP home-run candidate for Yankees: Luis García Jr.. The selection uses roster and season-stat inputs; it does not establish a confirmed batting lineup or favourable betting odds.

Chicago Cubs at San Diego Padres

Chicago Cubs starter Matthew Boyd faces San Diego's Michael King in a game featuring two pitchers with differing profiles. Boyd has a 3.91 ERA and 4.28 FIP over approximately 126.7 innings, while King has worked about 185.0 innings with a 3.21 ERA and 4.20 FIP. King's ERA and FIP are both better than Boyd's, giving him the edge as a pure run-prevention comparison.

Offensively, the Cubs bring a strong WP-estimated wOBA of 0.333 that outpaces San Diego's 0.313. On the team pitching side, San Diego's figures are better than Chicago's, with the Padres posting a 3.99 ERA and 4.27 FIP compared to the Cubs' 4.12 ERA and 4.67 FIP.

San Diego's injury list includes Miguel Andujar, Humberto Cruz and Yu Darvish, while Chicago's includes Tyler Austin, Brandon Birdsell and Ben Brown. With the Cubs holding a clear offensive advantage in wOBA but San Diego showing better team and starter run-prevention marks, the numbers point to a fairly balanced matchup with San Diego's pitching figures standing out as the stronger overall factor.

Statistical scope: MLB Stats API; 2026 regular season season-to-date; exact statistical through-date not supplied.

WP selection: Cubs +1.5. Confidence: Slight Lean.

The selection is supplied separately by WP. The comparisons above do not establish why the model made this selection.

WP home-run candidate for Cubs: Michael Conforto. The selection uses roster and season-stat inputs; it does not establish a confirmed batting lineup or favourable betting odds.

WP home-run candidate for Padres: Ty France. The selection uses roster and season-stat inputs; it does not establish a confirmed batting lineup or favourable betting odds.

Predictions are uncertain; no outcome is guaranteed. Check the picks page for the latest available selections.

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